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Adrenal Cortex and Medulla

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Topic updated on 12/16/16 4:43pm

Overview 
 
Primary Regulatory Control
Anatomy
Secretory products
Renin-angiotensin Zona glomerulosa Aldosterone
ACTH, hypothalamic CRH Zona fasciculata Cortisol and sex hormones
ACTH, hypothalamic CRH Zona reticularis Sex hormones (e.g. androgens)
Preganglionic sympathetic fibers Medulla Catecholamines (Epi, NE)
  • Glomerulosa (salt), fasciculata (sugar), reticularis (sex)
    • "The deeper you go, the sweeter it gets." 
Adrenal Circulation
  • Left adrenal
    • arterial supply from aorta
    • venous drainage to left adrenal vein then to left renal vein and finally to IVC
  • Right adrenal
    • arterial supply from right renal artery
    • Venous drainage to right adrenal vein then to IVC
  • Recall the same pattern for the left and right gonadal artery/vein
Selected Pathology
  • Pheochromocytoma
  • Neuroblastoma
  • Conn's syndrome
  • Cushing's syndrome
  • Addison's disease


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Qbank (1 Questions)

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(M1.EC.70) A 54-year-old woman appears in your office for a new patient visit. She reports a past medical history of hypertension, which she was told was related to "adrenal gland disease." You recall that Conn syndrome and pheochromocytomas are both conditions affecting the adrenal gland that result in hypertension by different mechanisms. Which areas of the adrenal gland are involved in Conn syndrome and pheochromocytomas, respectively? Topic Review Topic

1. Zona glomerulosa; zona fasciculata
2. Zona fasciculata; medulla
3. Zona glomerulosa; medulla
4. Medulla; zona reticularis
5. Zona fasciculata; zona reticularis

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