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Asplenia

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Topic updated on 01/25/17 8:14pm

Introduction
  • Asplenia = lack of spleen 
    • Congenital
      • rare
    • Acquired
      • post-operative 
      • functional asplenia
        • organ in place but no longer functional (e.g. patients with sickle cell disease)
Symptoms
  • Increased susceptibility to encapsulated bacteria 
    • e.g. H. influenzae, N. meningitidis, S. pneumoniae 
Treatment
  • Immunization against encapsulated organisms when possible 
  • Antibiotic prophylaxis (e.g. sickle cell patients) 
  • Regular influenza vaccination (to prevent secondary bacterial infection)


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