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Superantigens

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Topic updated on 04/07/16 9:02am

Introduction
  • Super antigens link T cell receptor to MHC class II leading to non-specific T-cell activation
    • results in massive cytokine release (e.g INF-γ)
      • examples
        • toxic-shock syndrome toxin-1 (TSST1)
        • streptococcal pyrogenic exotoxin


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