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Recombinant Cytokines

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Topic updated on 01/10/17 9:33pm

Overview
 
Clinical use
Cytokine
Mechanism
Thrombocytopenia  IL-11 ↑ Platelets
Thrombopoietin (THPO) ↑ Platelets
Bone marrow recovery Filgrastim (G-CSF) ↑ Granulocytes
Sargramostim (GM-CSF) ↑ Granulocytes
↑ Macrophages
Anemia
(particularly in renal failure)
Erythropoietin (EPO) ↑ RBCs
Renal cell cancer/
Melanoma (metastatic)
IL-2 ↑ Lymphocyte differentiation
↑ NK cells


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