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Antigen-Antibody Interactions

Topic updated on 05/23/17 12:16am

Introduction
  • Antibodies and antigens interact in order to
    • trap the offending microbe
    • generate an immune reponse in secondary lymphoid organs
  • Kinetics of antigen-antibody interaction
    • antigen excess
      • seen in the start of the infection due to
        • pathogen proliferation
        • antibody production has not yet started
    • equivalence
      • antibody production has become adequate and thus
        • free antibody or antigen cannot be detected
      • this corresponds to the window period for heptitis B antigen serologic studies
    • antibody excess
      • the infection has resolved and thus
        • there is more antibody than antigen
 


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