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Protozoa

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Topic updated on 03/13/15 10:44pm

Microbiology Overview
 
 
Protozoa Table 
 
GI infections
  Disease Treatment
Giardia lamblia Giardiasis (fatty diarrhea) Metronidazole
Entamoeba histolytica Amebiasis (bloody diarrhea, and red liver abscesses) Metronidazole
Cryptosporidium
  C. parvum
  C. isospora belli
  C. cyclospora cayetanensis
Diarrhea

Supportive only

Microsporidia Diarrhea Supportive only
CNS infections
Toxoplasma gondii Toxoplasmosis (brain abscesses in AIDS)
Congenital toxoplasmosis
Sulfadiazine
Pyrimethamine
Naegleria fowleri Primary amebic meningoencephalitis (PAM) Amphotericin B
Trypanosoma gambiense/rhodesiense African sleeping sickness Suramin
Melarsoprol
Acanthamoeba Granulomatous amebic encephalitis (GAE)
Keratitis (corneal infection)
Azoles
Visceral infections
Trypanosoma cruzi Chagas' disease Nifurtimox
Leishmania donovani Leishmaniasis Sodium stibogluconate
Hematologic infections
Plasmodium
  P. vivax
  P. ovale
  P. malariae
  P. falciparum
Malaria Chloroquine
Primaquine
Mefloquine
Babesia Babesiosis (like mild malaria) Quinine
STDs
Trichomonas vaginalis Vaginitis Metronidazole
 
Protozoa Introduction
  • Protozoa are single-celled eukaryotes
  • Cyst vs. trophozoite forms
    • in stressed environments, protozoa secrete a protective coat and shrink to a cyst form
      • cysts are ingested by humans, leading to disease
    • once inside a host, the protozoa convert back to their motile feeding form, the trophozoite form


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