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Streptococcus agalactiae (group B streptococci)

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Topic updated on 12/15/16 2:02pm

Overview

Introduction
  • Classification
    • bacteria
      • Gram-positive cocci
        • Streptococcus
          • Streptococcus agalactiae (group B strep)
  • Pathogenesis
    • transmission
      • perinatal
        • increased risk with prolonged labor after rupture of membranes
    • reservoir
      • vagina
        • 15-20% of women are carriers
      • GI tract
    • virulence factors
      • capsule is pathogenic
      • lipotechoic acid of cell wall - repels cationic antibicrobial peptides (innate immune system)
Diseases
  • Neonatal septicemia
    • most common cause
  • Neonatal meningitis
    • most common cause
  • Neonatal pneumonia
  • Neonatal osteomyelitis
  • "Babies' Brains get Beta-hemolytic, Bacitracin Blocking group B during Belabored delivery"
Laboratory
  • Bacitracin resistant
  • β-hemolytic
  • Hydrolyze hippurate
  • CAMP test positive
Treatment
  • Ampicillin
    • with aminoglycoside or cephalosporin
  • Prophylaxis during high-risk deliveries
    • intrapartum ampicillin for mom after week 35


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