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Gardnerella vaginalis

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Topic updated on 06/13/17 5:17pm

Introduction
  • Classification
    • Bacteria
      • Gram-variable
        • Gardnerella
          • G. vaginalis
  • Pathogenesis
    • transmission
      • endogenous
    • reservoir
      • vagina
    • molecular biology
      • flourishes when
        • normal flora gets disturbed
        • pH increases
        • ↓ vaginal Lactobacillus
Diseases
  • Vaginosis
    • gray vaginal discharge
      • fishy smell
    • noninflammatory
    • nonpainful
    • synergy with Mobiluncus
      • an anerobe
Laboratory
  • Diagnosis
    • clue cells seen in vaginal smears
      • vaginal epithelial cells covered with bacteria (shown)
    • pH > 4.5
  • Characteristics
    • gram-variable
      • pleomorphic
    • catalase-negative
    • oxidase-negative
    • facultative anaerobe
  • Formerly Haemophilus vaginalis
    • separated from genus because it does not require X or V factor for growth
Treatment
  • Metronidazole


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