questions 1

Nystatin

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Topic updated on 11/07/17 1:51pm

Introduction
  • Classification
    • antifungal
      • polyene
        • nystatin
  • Drugs
    • nystatin
Mechanism
  • Action 
    • functions by disrupting fungal cell membrane permeability
      • see Amphotericin B 
Uses
  • Candidiasis
    • oral (thrush), esophageal, gastric
      • "nystatin, swish and swallow"
    • vaginal
    • diaper rash
  • Treats skin and mucous membranes topically, and treats GI tract "topically" as it passes through the body without being absorbed
Adverse effects
  • Too toxic to be given IV
Pharmacology
  • Not orally absorbed


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