questions 1

Proteus

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Topic updated on 09/11/17 2:22pm

Introduction
  • Classification
    • Bacteria
      • Gram-negative bacilli
        • The Enterics
          • facultative anaerobes
            • Enterobacteriaceae
              • non-lactose fermenting
              • Proteus
                • P. mirabilis
                • P. vulgaris
  • Pathogenesis
    • transmission
      • endogenous
    • reservoir
      • human colon
      • water and soil
    • molecular biology
      • urease raises urine pH
        • causes kidney stones
      • motility may aid entry to bladder
      • endotoxin causes fever and shock
Diseases
  • UTI
  • Septicemia
  • Kidney stones
Laboratory
  • Swarming motility
    • peritrichous flagella
      • pertrichous = uniformly distributed over surface of bacteria
    • highly motile
  • Urease positive 
  • Non-lactose fermenting
Treatment
  • Fluoroquinolones
  • TMP-SMX
  • Third-generation cephalosporin


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