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Cerebellum

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Topic updated on 11/02/15 8:52am

Overview
  • Function
    • provides stimulatory feedback to contralateral motor cortex
      • modulates movement
      • allows cerebral motor cortex to correct a movement based on feedback from the periphery
    • assists in coordination and balance
  • Functional anatomy
    • input
      • receives contralateral cortical input via middle cerebellar peduncle
      • receives ipsilateral proprioceptive via inferior cerebellar peduncle
      • input nerves consist of climbing and mossy fibers
    • output
      • Purkinje fibers from cerebellar cortex synapse on deep cerebellar nuclei
        • deep nuclei
          • lateral → medial
            • Dentate, Eboliform, Globose, and Fastigial
              • "Don't Eat Greasy Foods"
          • lateral nuclei assist in voluntary movement of extremities
          • medial nuclei assist in balance, truncal coordination
      • deep nuclei output to contralateral cerebral motor cortex via superior cerebellar peduncle
  • Pathology
    • damage to cerebellar hemisphere
      • symptoms of ipsilateral intention tremor and limb ataxia
      • tendency to fall towards side of lesion
    • damage to cerebellar vermis
      • symptoms of truncal ataxia and dysarthria


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