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(M1.BC.22) A 55-year-old African American lawyer presents to your office with complaint of fatigue, back pain and dark urine. He had just started a course of trimethoprim-sulfamethoxazole for UTI. His CBC shows anemia and the peripheral blood smear is as shown in Figure A. Which pathway below is defective in this man? Topic Review Topic
FIGURES:   A          

1. Conversion of glucose to glucose-6-phosphate (G6P)
2. Conversion of G6P to glucose-1-phosphate
3. Conversion of G6P to 6-phosphogluconate
4. Conversion of G6P into fructose-6-phosphate
5. Conversion of glucose into G6P

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