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(M1.BC.72) Expression of an mRNA encoding for a soluble form of the Fas protein prevents a cell from undergoing programmed cell death. However, after inclusion of a certain exon, this same Fas pre-mRNA eventually leads to the translation of a protein that is membrane bound, subsequently promoting the cell to undergo apoptosis. Which of the following best explains this finding? Topic Review Topic

1. Base excision repair
2. Histone deacetylation
3. DNA missense mutation
4. Post-translational modifications
5. Alternative splicing

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