questions 1

Listeria monocytogenes

Author:
Topic updated on 10/21/16 7:34am

Introduction
  • Classification
    • Bacteria
      • Gram-positive bacilli
        • non-spore forming
          • Listeria
            • Listeria monocytogenes
  • Pathogenesis
    • transmission
      • foodborne
      • crosses placenta
      • vaginal transmission during birth
    • predisposing factors for infection
      • immunologic immaturity
    • reservoir
      • cold growth in cheese, deli meats, coleslaw, hotdogs
      • unpasteurized milk
      • animals, plants, soil
    • molecular biology
      • the only Gram-positive bug with endotoxin
      • listeriolysin O
        • evades killing by phagosome
      • facultative intracellular parasite
        • cell-mediated immunity required to fight infection
        • explains why immunocompromised are at higher risk
Diseases
  • In pregnant women
    • amnionitis
    • septicemia
    • spontaneous abortion
  • In infants
    • granulomatosis infantiseptica
      • in utero transmission
      • signs may be non-specific but include: septicemia, meningitis, pneumonia
      • multiple abscesses and pale granulomas on skin and other organs
    • neonatal meningitis
  • In immunocompromised patients
    • meningitis
      • most common cause of meningitis in adults with cancer and renal transplant patients
    • septicemia
  • In healthy individuals
    • mild gastroenteritis
Laboratory
  • Tumbling motility in broth at 22 degrees C
    • can be cultured as low as 4 degrees C
  • Actin jet motility in cells
  • Small
  • β-hemolytic
    • appears like beta-hemolytic Strep on blood agar
  • Gram-positive
  • Non-spore forming
Treatment
  • Ampicillin
    • add gentamicin for immunocompomised
  • Pregnant women should not eat cold deli foods


  RATE CONTENT
5.0
AVERAGE 5.0 of 2 RATINGS

Qbank (0 Questions)

Sorry, this question is only available for Study Plan members.
Access to 600+ Questions not available in Free Qbank



Evidence & References Show References




Topic Comments

Subscribe status: