- crosses placenta
- vaginal transmission during birth
- predisposing factors for infection
- cold growth in cheese, deli meats, coleslaw, hotdogs
- unpasteurized milk
- animals, plants, soil
- molecular biology
- the only Gram-positive bug with endotoxin
- listeriolysin O
- evades killing by phagosome
- facultative intracellular parasite
- cell-mediated immunity required to fight infection
- explains why immunocompromised are at higher risk
- In pregnant women
- spontaneous abortion
- In infants
- granulomatosis infantiseptica
- in utero transmission
- signs may be non-specific but include: septicemia, meningitis, pneumonia
- multiple abscesses and pale granulomas on skin and other organs
- neonatal meningitis
- In immunocompromised patients
- most common cause of meningitis in adults with cancer and renal transplant patients
- In healthy individuals
- Tumbling motility in broth at 22 degrees C
- can be cultured as low as 4 degrees C
- Actin jet motility in cells
- appears like beta-hemolytic Strep on blood agar
- Non-spore forming
- add gentamicin for immunocompomised
- Pregnant women should not eat cold deli foods
AVERAGE 5.0 of 2 RATINGS
Qbank (0 Questions)
Level of Evidence 5 and Other Journal Articles (includes Case Reports, Expert Opinions,
Personal Observations, and Biomechanic Studies)
Tunkel AR, Scheld WM. Issues in the management of bacterial meningitis. Am Fam Physician. 1997 Oct 1;56(5):1355-62. Review.
PMID:9337758 (Link to Abstract)
Hamon M, Bierne H, Cossart P. Listeria monocytogenes: a multifaceted model. Nat Rev Microbiol. 2006 Jun;4(6):423-34. Review.
PMID:16710323 (Link to Abstract)
- First Aid for the USMLE STEP 1. Le, Tao. New York: McGraw-Hill Medical, 2013.
- Rapid Review Pathology Revised Reprint. Goljan, Edward. New York: Mosby, 2011.
- Clinical Microbiology Made Ridiculously Simple 5th Ed. Gladwin, Mark. Miami: MedMaster Inc, 2011.
- medEssentials for the USMLE Step 1. Manley, Michael. New York: Kaplan Publishing, 2012.
- Katzung & Trevnor's Pharmacology Examination and Board Review. Trevor, Anthony. New York: Lange Medical Books, 2012.