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Contrast-Induced Nephropathy

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Topic updated on 12/22/15 9:58pm

Introduction
  • Creatinine spike within 24 hours of CT imaging contrast administration secondary to tubular damage
  • Patients at risk
    • diabetics
    • chronic renal insufficiency
      • measure with high baseline creatinine
  • In high risk patients use alternative studies or CT without ionic contrast agents
Prevention, Prognosis, and Complications
  • Normally has return of renal function by 5-7 days
  • Proper pre-contrast treatment
    • IV hydration
    • N-acetyl cysteine
    • fenoldopam
    • discontinue NSAIDs
    • prednisone
      • only in those to have known allergy to contrast but does not prevent nephropathy


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